Cognizant Technology Solutions is seeking for Techno Functional SME with core background in Bioinformatics, Transcriptomics and GCP Cloud who could join in our team of IT professionals in a permanent role.
Role: Bioinformatics Engineer – Single-cell & Bulk Transcriptomics
Skill set: Bioinformatics, scRNA-seq, Bulk RNA-seq, GCP, Pipeline Engineering
Must have skill:
· Experience processing scRNA-seq and bulk RNA-seq datasets (10x Genomics, SMART-seq)
· Workflows: Cell Ranger, STARsolo, Kallisto Bustools, Alevin/Alevin Fry, Seurat/Scanpy
· Bulk RNA-seq tools: STAR, HISAT2, Salmon, Kallisto, FastQC, Picard, DESeq2, edgeR, limma
· Pipeline capabilities: FASTQ/BCL ingestion, QC, trimming, alignment/pseudo-alignment
· Gene/transcript quantification, normalization, batch correction and feature selection
· Experience in clustering, dimensionality reduction, DE analysis and trajectory inference
· Pathway enrichment, gene signature identification and biological interpretation
· Integration with metadata (cell types, clusters, experimental conditions)
· Experience integrating immune repertoire pipelines (CDR extraction, clonotype metrics)
· Python/R expertise and workflow engines (Nextflow, Snakemake, Cromwell)
· Containerization (Docker/Singularity) and GCP services (BigQuery, GCS, Compute Engine, Composer, Pub/Sub)
· CI/CD implementation for pipeline automation
Good to have:
· Experience with transcriptomics repositories (GEO, ArrayExpress, Human Cell Atlas)
· Infrastructure as Code (Terraform)
· Experience in enterprise-scale bioinformatics platforms
Responsibilities:
· Design and implement pipelines for transcriptomics data processing and integration
· Perform clustering, trajectory, differential expression and pathway analysis
· Generate standardized outputs compatible with Seurat, Scanpy, DESeq2, edgeR
· Integrate transcriptomics with immune repertoire datasets
· Develop scalable, modular pipelines with audit logging
· Deploy pipelines in GCP using containerized workflows
· Implement CI/CD for reproducible pipeline execution
· Validate dataset integrity and biological correctness
· Harmonize metadata and map to enterprise models
· Create documentation and support demos/workshops
About Cognizant:
Cognizant (Nasdaq: CTSH) is an AI Builder and technology services provider, bridging the gap between AI investment and enterprise value by building full-stack AI solutions for our clients. Our deep industry, process and engineering expertise enables us to build an organization’s unique context into technology systems that amplify human potential, drive tangible outcomes and keep global enterprises ahead in a fast-changing world. See how at cognizant.ai or @cognizant.
Additional employment information
Compensation information is accurate as of the date of this posting. Cognizant reserves the right to modify this information at any time, subject to applicable law.
Applicants may be required to attend interviews in person or by video conference. In addition, candidates may be required to present their current state or government issued ID during each interview.
Cognizant is an equal opportunity employer. Your application and candidacy will not be considered based on race, color, sex, religion, creed, sexual orientation, gender identity, national origin, disability, genetic information, pregnancy, veteran status or any other characteristic protected by federal, state or local laws.
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